Date: 22/01/1921 
Competition: Central League
 Manchester United Reserves |
6 - 1 Full-Time |
 Southport |
| Goalscorers | ||
 WIlliam Rigby |
||
Line-Ups
| - | John Thompson |
| - | Billy Garner |
| - | Billy Glover |
| - | Lal Lightburn |
| - | Billy Little |
| - | W Littleton |
| - | Nat Rawlins |
| - | WIlliam Rigby |
| - | Billy Semple |
| - | Harry Sinclair |
| - | Tommy 'Topping' Sinclair |