| 1894 |
Lancashire League Medal Competition |
| Southport | South Shore | 2 - 1 |
| 1900 |
Lancashire League |
| Earlestown | Southport | 4 - 2 |
| 1906 |
Lancashire Combination |
| Southport | Barrow | 3 - 2 |
| 1912 |
Central League |
| Glossop North End Reserves | Southport | 1 - 1 |
| 1917 |
War-Time: League |
| Southport | Port Vale | 3 - 1 |
| 1920 |
Lancashire Junior Cup |
Semi Final Replay | Southport | Chorley | 2 - 0 |
| 1923 |
Football League |
D3N | Southport | Darlington | 2 - 1 |
| 1923 |
West Lancashire League |
| Horwich Central | Southport Reserves | 0 - 1 |
| 1934 |
Football League |
D3N | Southport | Mansfield Town
| 3 - 3 |
| 1934 |
Lancashire Combination |
| Rochdale Reserves | Southport Reserves | 2 - 1 |
| 1940 |
Combination Cup |
| Southport Reserves | Leigh Rmi Reserves | 3 - 1 |
| 1940 |
War-Time: League |
| Burnley | Southport | 7 - 3 |
| 1947 |
Lancashire Combination |
| Southport Reserves | Fleetwood | 0 - 3 |
| 1951 |
Lancashire Combination |
| Nelson | Southport Reserves | 3 - 2 |
| 1951 |
Football League |
D3N | Southport | Bradford (Park Avenue) | 2 - 4 |
| 1952 |
Lancashire Combination |
| Southport Reserves | Morecambe | 1 - 2 |
| 1962 |
Lancashire Combination |
| Oldham Athletic Reserves | Southport Reserves | 4 - 3 |
| 1968 |
Football League |
D3 | Oldham Athletic | Southport | 2 - 0 |
| 1968 |
Lancashire League |
| Southport A | Stockport County A | 2 - 3 |
| 1970 |
Northern Floodlit Challenge Cup |
| Southport Reserves | Shrewsbury Town
Reserves | 1 - 0 |
| 1971 |
Northern Floodlit Challenge Cup |
| Port Vale Reserves | Southport Reserves | 0 - 3 |
| 1971 |
Northern Floodlit League |
| Port Vale Reserves | Southport Reserves | 0 - 3 |
| 1973 |
Football League |
D4 | Southport | Aldershot | 3 - 1 |
| 1974 |
Lancashire Senior Cup |
1 Replay 2 | Morecambe | Southport | 1 - 0 |
| 1990 |
Northern Premier League |
| Caernarfon Town | Southport | 0 - 1 |
| 1996 |
FA Trophy |
1 | Halifax Town | Southport | 2 - 1 |
| 2001 |
National League |
| Yeovil Town | Southport | 0 - 1 |
| 2007 |
National League |
| Crawley Town | Southport | 2 - 1 |
| 2018 |
National League |
North | Southport | Stockport County | 3 - 1 |
| 2025 |
Liverpool Senior Cup |
QF | City of Liverpool | Southport | 0 - 1 |
| 2026 |
National League |
North | South Shields | Southport | |